Psychoneuroimmunology (PNI)

When everything affects everything,
one part is not enough.

PNI explores how habits, stress, sleep, digestion, metabolism and immune regulation interact.

Cristóbal Becerril, who leads psychoneuroimmunology at ETRYUM, at the clinic.

It may start here

You do not need to know
which system to look at first.

The assessment starts with what you notice, what life demands of you and what you want to recover or prevent.

01

You perform, but recover less well

You maintain the pace at work or in sport, but sleep, energy or adaptability no longer respond in the same way.

02

You sleep, but do not feel restored

Your schedule, mental load, light, activity and diet may be interfering with the same recovery process.

03

Digestion shapes your day

Digestive discomfort, food tolerance or changes in bowel habits begin to affect your energy and routines.

04

You want to act earlier

You want to understand trends, risk factors and modifiable habits before a problem limits your life.

A symptom is a signal.
Context completes the story.

The body responds as a network. PNI organises that information to set clinically meaningful priorities.

  1. 01

    Stress and regulation

    Psychosocial load, neuroendocrine response and adaptation strategies.

  2. 02

    Sleep and rhythms

    Timing, rest, light exposure and physiological recovery.

  3. 03

    Digestion

    Habits, symptoms, digestive function and the gut-brain axis.

  4. 04

    Metabolism

    Energy, body composition, activity and available biomarkers.

  5. 05

    Immunity and inflammation

    Modifiable factors that influence response and resolution.

  6. 06

    Hormonal balance

    Sleep, stress, nutrition and activity in their neuroendocrine context.

The process

Not a pre-set
protocol.

The plan is built after assessing the case and adjusted as it evolves.

  1. 01

    Listen

    Your reason for attending, history, goals, medication, supplements and personal context.

  2. 02

    Connect

    Habits, nutrition, sleep, stress, activity, digestion, recovery and available tests.

  3. 03

    Prioritise

    Define what matters, what can be modified and what needs medical assessment.

  4. 04

    Intervene

    Set realistic goals and progressive lifestyle strategies within the scope of PNI.

  5. 05

    Review

    Assess adherence, symptoms, objective measures and response before adapting the plan.

Health does not mean never responding to stress. It means adapting, recovering regulation and becoming available again.

At ETRYUM, this biological flexibility becomes a practical principle: do not accumulate interventions, but understand which mechanism deserves attention and how its progress can be assessed.

Areas of intervention

A plan built around
your priority.

These are not fixed packages. Areas are selected and combined according to the initial assessment, goals and progress.

01

Digestive health and the gut-brain axis

Dietary, behavioural, sleep and stress factors related to digestive function.

02

Stress and neuroendocrine regulation

Load, habits, recovery and adaptation strategies suited to your context.

03

Sleep and circadian rhythms

Timing, light exposure, routines and factors that interfere with restorative sleep.

04

Metabolism and body composition

Nutrition, activity, sleep, stress and metabolic trends that may be modified.

05

Immunity and inflammation

Habits and context associated with inflammatory processes and adaptability.

06

Recovery under high demand

Sleep, load, nutrition, stress and recovery for athletes and high-demand professionals.

Versions

The same PNI perspective.
Adapted to your context.

The plan is built around what your life demands and the stage you are in.

Sport

Athletes and high performance

Who it is for: People who train or compete and notice they recover worse, sleep worse or perform below expectations.

What it focuses on

  • Sleep, load and recovery
  • Food and digestion around training
  • Coordination with sports medicine and physiotherapy
Women

Women and hormonal stages

Who it is for: Women whose hormonal stages affect their energy, rest, digestion or mood.

What it focuses on

  • Rhythms, sleep and stress at each stage
  • Adapted food and habits
  • Coordination with the physician when needed
High demand

Professionals under heavy load

Who it is for: Professionals who sleep but don’t rest, and feel daily demands are already taking their toll.

What it focuses on

  • Stress load and regulation
  • Realistic routines for complex schedules
  • Energy and capacity to adapt

Clinical judgement

Integration also means
knowing when to refer.

PNI does not replace medical diagnosis or treatment. If warning signs, abnormal results or a concern requiring investigation appear, the case is coordinated with the appropriate professional.

Tests and biomarkers are interpreted in context. An isolated value does not become a diagnosis or a promise of results.

Portrait of Cristóbal Becerril, who leads psychoneuroimmunology at ETRYUM.

Your specialist

Cristóbal Becerril

Psychoneuroimmunology
Stress · Sleep · Metabolism · Digestive health

A registered nurse (Alicante College of Nursing, no. 15778) with postgraduate training in clinical psychoneuroimmunology. Cristóbal brings together the person's history, habits, environment and available clinical information to build an individual, progressive and reviewable plan. He coordinates with medicine, physiotherapy and other professionals when needed.

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Frequently asked questions

Before you begin.

See all frequently asked questions

Do I need a diagnosis to request a PNI assessment?

No. You may attend because of a group of symptoms, difficulty recovering or a preventive goal. The first assessment organises the information and identifies the appropriate next step.

What should I bring to the first consultation?

Any recent reports, blood tests or investigations you already have, plus an up-to-date list of medication and supplements. You do not need new tests before speaking to the team.

Does PNI replace a medical consultation?

No. PNI works on habits and modifiable factors within its scope. Diagnosis, prescribing and medical treatment remain the responsibility of a physician and are coordinated when appropriate.

Does everyone receive the same protocol?

No. The areas, intensity and duration are decided after assessment and adapted to response, adherence and goals.

Can it support athletes or high-demand professionals?

Yes. It can assess sleep, habits, load, stress and recovery, coordinating with sports medicine or physiotherapy when needed.

Can I send medical information through the form?

No. The form is only for requesting contact and arranging an assessment. Clinical documents are collected later through the appropriate channels.

Comprehensive PNI assessment

Start by understanding
what is connected.

Leave your details to request an assessment with Cristóbal Becerril. The team will contact you personally to guide you and arrange the appointment.

Prefer to speak directly? +34 621 172 479 · info@etryum.com

Basic information on data protection

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  • A person from our team answers you
  • No obligation
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